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Ecdysone is a steroid hormone that regulates the procedures of MOLTING or ecdysis in insects. It may promote cell growth, activate dermal cell division, plus promote protein synthesis within the human body.
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Ecdysone is a 6-oxo steroid which is 5beta-cholest-7-en-6-one substituted simply by hydroxy groups at opportunities 2, 3, 14, 22 and 25 respectively (the 2beta, 3beta, 22R stereoisomer). It is a steroid prohormone of the major insect moulting hormone 20-hydroxyecdysone. It provides a role as the prohormone. It is the 2beta-hydroxy steroid, a 14alpha-hydroxy steroid, a 22-hydroxy anabolic steroid, a 25-hydroxy steroid, the 6-oxo steroid, a 3beta-sterol and an ecdysteroid. This derives from a hydride of a 5beta-cholestane.
Ecdysone acts on the individual body to promote collagen synthesis, anti-arrhythmia, anti-fatigue; advertise cell growth, stimulate skin cell division, eradicate bad cholesterol in the body; reduce blood fat, inhibit blood sugar rise; pass through energy, dehumidification and analgesia, and so on. Physiological activity. It is a organic anti-cancer preparation.
Since the introduction of dew ecdysone within 1976, tablets, injections and ointments have been created. Folk rheumatoid arthritis, rheumatoid arthritis patients based on a symptoms have good curative effect. The active ingredient 20-hydroxyecdysterone has been clinically tested to have direct hypoglycemic impact, as well as the total effective price for type II diabetes is 84%. It will be especially effective in improving the symptoms of “three more and one less” in diabetic patients.
In sports care products, ecdysone has a important capability to assemble protein chains by increasing amino acids, thereby stimulating protein activity in muscle cytoplasm, and this ability goes back again to the translation plus migration process of proteins growth.
Ecdysone is not only good for wellness but also safe. This helps stabilize cells within cortisol injury, normalizes energy synthesis steps (ATP plus sarcosine) and increases liver organ function to ensure that organisms can quickly adapt to environmental and pressure changes.. The safety, after more compared to 50 studies, showed that ecdysone has no part effects, no interaction with hormones, and extremely lower levels of toxicity.
When tested at the ICN Biochemical Laboratory in 1998, the data showed that ecdysone had to show an ultra-high dose associated with 6400 mg/kg. Moreover, within the endocrine test containing testo-sterone, cortisol, insulin, cortisol, human growth hormone and luteinizing hormone, there was clearly no report of the a result of ecdysone on the mammalian hormonal system.
Ecdysone is a steroidal prohormone of the major pest molting hormone 20-hydroxyecdysone, which is secreted from the prothoracic glands. Insect molting human hormones (ecdysone and its homologues) are generally called ecdysteroids. Ecdysteroids act as moulting hormones of arthropods but additionally occur in other associated phyla where they may play different roles. Within Drosophila melanogaster, an boost in ecdysone concentration induce the expression of genes coding for proteins that will the larva requires, and it also causes chromosome puffs (sites of high expression) in order to form in polytene chromosomes. Recent findings in the particular laboratory of Chris Q. Doe have found the novel role of this particular hormone in regulating temporary gene transitions within nerve organs stem cells of the particular fruit fly. Ecdysone plus other ecdysteroids also appear in many plants mainly as a protection agent (toxins or antifeedants) towards herbivorous insects.
These phytoecdysteroids are actually reputed to have got medicinal value and are part of herbal adaptogenic treatments like Cordyceps, however an ecdysteroid precursor within plants has been displayed to have cytotoxic properties.
Within the sericulture, it is employed to promote the reducing of the silkworm age group, the upper clusters are neat, and promote the particular silkworm crusting; ecdysone is usually a substance necessary regarding the aquatic crustaceans, shrimp, crab growth and growth, and shelling and metamorphism. The main raw material associated with the chitin is suited to the artificial breeding associated with aquatic crustaceans and locusts such as shrimps plus crabs. After adding this particular product, the shrimp plus crab can be easily shelled, and the uniformity of shelling and shrimp can be promoted. It effectively avoids mutual eliminating among individuals and drastically increases the survival price and commodity specifications associated with the culture.
In makeup, it is generally utilized following the special treatment associated with high-purity ecdysone, also known as "ecdysterone", which will be a pure white crystalline powder or perhaps a colorless clear crystal using a single element and no allergic attack in order to the skin. Strong permeability, can be quickly soaked up by the skin in the liquid state; effective compound that can enhance cellular metabolism and activation, provides good exfoliation, whitening plus whitening effect, facial melasma, traumatic dark spots, freckles, Melanin has a good mending effect, and this also has obvious results on acne. It really is a lot higher in promoting the particular synthesis of collagen healthy proteins than any product upon the present market.
