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Aloe barbadensis has edibility and beauty and healthcare Benefits

Aloe Vera Plants

Aloe vera is a quite common green plant that purifies the air. The gel inside the leaves can not only be used to treat mild burns and scalds, but also to remove phlegm. Some skincare products on the market are made of the gel from the leaves. But do you know that Aloe vera can also be used for consumption.

There are 3,000 varieties of aloe vera in the world, however not all aloe vera can be eaten. The aloe variety that can be eaten is relatively little, just only about 10 varieties in the world. There are three kinds of aloe vera which are relatively largely planted, namely Aloe barbadensis, Aloe arborescens, and China aloe. The Aloe arborescens have large and thick leaves, extremely rich aloe vera gel, and remarkable beauty and health care effect.

The molecular weight of Aloe barbadensis polysaccharide is up to 450,000, which is more than 40 times that of Aloe vera. It tends to grow in soft soil and has high reuqirement for drainage performance. The soil for Aloe barbadensis is relatively more porous and low-binding than ordinary aloe vera.   

Aloe vera is quite afraid of cold, so its most suitable growth environment is a mild environment. If the temperature in the environment is too low, it is prone to frostbite. It has long grown in a frost-free environment all year round.

As a herb, Aloe barbadensis also needs enough water, but it should be kept away from water, especially in the rainy season in the south. If Aloe barbadensis faces much ponding and poor drainage, it will easily get its rhizome rotten and turns yellow. 

Aloe barbadensis has a large demand for light. If given enough light every day, it will grow stronger, more beautiful, and keep it green forever. If the fertilizer is applied properly, Aloe barbadensis will grow easier.

Aloe Barbadensis Leaf Extract(Aloe Vera Leaf Extract)

Hello, let’s get to know Aloe vera and one of its commonly used varieties---Aloe barbadensis.

Aloe vera has many synonyms: A. Barbadensis Mill. , Aloe indica Royle, Aloe perfoliata L. var. Vera and A. vulgaris Lam. Its common names include Chinese Aloe Vera, Indian Aloe Vera, Real Aloe Vera, Barbados Aloe Vera, Burnt Aloe Vera, and First Aid Plant. The modifier word aloe means "true" or "real".

A. vera is considered to be limited to the southwestern part of the Arabian Peninsula. However, it has been widely cultivated around the world and has been naturalized in North Africa, Sudan and neighbouring countries as well as the Canary Islands, Cape Verde and Madeira. It is also naturalized in the wild areas of southern Spain, especially in the Murcia region, the only naturalized place in Europe.

Aloe barbadensis

The species was introduced to various regions of China and Southern Europe in the 17th century. It is widely naturalized elsewhere, occurring in Australia, South America, Mexico, the Caribbean and the temperate and tropical regions of the southeastern United States. The current distribution may be the result of human cultivation.

Aloe vera has several uses which are as follows.

1.The study

Although there is little scientific evidence to show the efficacy or safety of aloe vera extract in cosmetics or medicinal purposes, the cosmetics and alternative medicine industries often require aloe's soothing, moisturizing and healing properties. There isn't enough evidence that aloe vera can be used to treat wounds or burns, and there is no topical application to treat genital herpes or psoriasis. The 2014 Cochrane review found insufficient evidence for topical treatment or prevention of phlebitis caused by intravenous infusion.

Aloe Vera Gel is used commercially as a component of yogurt, beverages and some desserts, but at certain high doses, its toxicity can be severe when taken orally.

2.Dietary Supplements

Aloin is a compound found in exudates of some aloe species and is a common ingredient in over-the-counter (OTC) laxatives in the United States until the US Food and Drug Administration banned it in 2002 because the company that produced it failed to provide necessary safety data. Aloe vera is potentially toxic, and side effects occur at certain dose levels when ingested or topically applied. Although the toxicity of removing aloin during treatment can be less than the side effects that aloe contains aloe in excess.

Aloe vera juice is sold on the market to support the health of the digestive system, but there is neither scientific evidence nor regulatory approval to support this claim. The extracts and amounts typically used for such purposes which appear to be dose-dependent toxic effects.

3.Traditional medicine

Aloe vera is used for skin care in traditional medicine. In Ayurvedic medicine, it is called kathalai, so is the agave extract. The earliest record of aloe vera appearing in the Ebers Papyrus of 16th century BC, and the natural history of De Materia Medica and Pliny the Elder of Dioscorides were both written in the middle of the first century AD. Moreover, it is also written in Juliana Anicia Codex in 512 AD.

4.Commodity

Aloe vera is used for facial tissues and is promoted as a moisturizer and anti-irritant to reduce the friction of the nose. Cosmetic companies often add aloe vera juice or other derivatives to cosmetics, tissues, moisturizing cream, soaps, sunscreens, incense, shaving creams or shampoos. A review of the academic literature indicates that it is included in many hygiene products because it has a "moisturizing effect".

 


Cosmetic Ingredients Introduction 03 - Tonymoly bb cream the seasoning sauce

Next, we will talk about Aloe barbadensis.

Aloe barbadensis, a succulent plant of the aloe, is also known as Aloe vera or American Aloe.

Aloe barbadensis (scientific name: Aloe vera (L.) Burm.f.) is a plant of the genus Aloe. It has short stems, erect and inseparate branches, large and thick leaves, juicy and succulent component, narrowly-lanceolate shape, and broad base. When the plants are immature, the leaves grow in two rows, and when grown, they are rosette-like. The leaves are 60-80 cm long and 9-12 cm wide. The calyx is 80-100 cm tall, keeping a racemose, from leaf axil. Small flowers exhibit cylindrical, with a narrow yellow base, blossoming in winter and spring. Aloe flower is a Chinese medicine name.

Aloe barbadensis is mainly produced in Curacao, Aruba and Bonaire near the northern shore of South America. The Guangxi Citrus Research Institute and the Guangxi Fruit and Vegetable Research Institute introduced and cultivated it in 1991. It enjoys warmth with high temperature resistance, and cannot suffer cold. Leaves can be used in medicine, for its clearing heat, laxative, insecticide properties; attending constipation due to body out of balance, women's amenorrhea, pediatric epilepsy, infantile malnutrition and parasitic amassment, phlegm, acne, atrophic rhinitis, and scrofula.

Not all aloe vera can be used for beauty. Only one variety called "Aloe barbadensis" can be used for beauty. Moreover, it is one of the few edible species in Aloe, and its products are widely used in food, beauty, health care, medicine and other fields. However, aloe vera also has certain toxicity, and it is not suitable for pregnant women and infants. Ordinary people should consume less than 30 grams of aloe vera gel per day. Allergic reactions to aloe include skin redness, roughness, etc.. Mild allergic reactions include nausea, vomiting, diarrhea and other symptoms, while severe allergy cases can cause acute nephritis.

Aloe vera has always been associated with herbs, but it is not known when it is used for treatment. The early records of the use of Aloe Vera include the "Ebers Papyrus" in 16th century BC, the Dios Collier's "Pharmacology" and the old Pliny's "History" in the middle of the 1st century, and "Juliana Anisia Transcript." in 512 AD. Aloe barbadensis is non-toxic. Apart from aloin with no side effect, inhaling too much Aloe barbadensis containing aloin will cause many side effects. However, they are still widely used in China, Japan, Russia, South Africa, the United States, Jamaica and India.

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A study on clinical, ultrasonography and haematology of aglepristone-induced mid-gestation pregnancy terminations for rabbits

Aglepristone is used as a safe abortion drug for cats, dogs and rabbits. Although finding no serious side effects of it, we also have no information available about its effects on haematological  parameters. 

For the first time clinical and ultrasonographic features  and haematological profiles were evaluated in rabbits treated with aglepristone 15 and 16 days after mating. Ten healthy New Zealand White female rabbits of 10–14 month-old were mated with fertile  males and their pregnancies were confirmed by ultrasound after 15 days.  Among them, 5 were treated  with aglepristone (test group, n=5) while the remaining five (control group, n=5) were treated with a saline solution (0.9% NaCl). The treatment dosage was 10 mg/kg body weight, administered subcutaneously once daily on two consecutive days (day 15 and 16 after copulation). Ultrasonographic, clinical and haematological examinations were conducted daily. Aglepristone treatment induced embryonic fluid resorptions without foetal death in mid-gestation terminations. After ultrasonographic and haematological examinations done, aglepristone was confirmed to be a safe abortion drug for rabbits.

As a progesterone receptor blocker, the function of aglepristone has previously been studied in mid-term termination of pregnancy and the prevention of implantation in rabbits. Aglepristone is a synthetic steroid with anti-progesterone activity. Furthermore, it is widely used as the first licensed antiprogestin in small animal practice in most European, Latin American and Pacific countries. Although aglepristone is applied to cats and dogs, there are fully-testified side effects. 

As is reported, there are anorexia,  necrosis, itching at injection sites and a decline in body temperature. Transient and reversible haematological changes have been reported in 4.5% of dogs after the application of aglepristone, including neutrophilia, neutropaenia, thrombocytosis, haematocrit variation, lymphocytosis and lymphopaenia. 

However, for rabbits, aglepristone’s abortifacient effects and prevention of implantation have no clinical side effects. Even in the future mating behavior, pregnancy and  parturition rates, are well recorded. Embryonic or foetal development and placental  growth can be testified by ultrasonographic examinations. Pregnancy  can be confirmed through ultrasonography based on the detection of embryonic vesicles on the 6th day of pregnancy and heartbeat of an embryo on the 14th day after mating in rabbits. 

Ultrasonography is also an important method for monitoring embryonic or foetal viability, so it is useful to determine foetal mortality in induced abortions in rabbits. Haematological examinations, in turn, are used to examine general health and physiological changes in animals. During treatment, routine haematological monitoring is suggested to enable identification and control of any toxic side effects of the medication. Although finding no serious side effects of aglepristone clinically, we alos get no information on haematological changes during aglepristone application in rabbits. This study therefore aimed at describing the clinical features and haematological profiles after aglepristone-induced abortions by monitoring the foetus, foetal  membranes and embryonic vesicles ultrasonographically during the  abortion process.

Aglepristone

Inhibition of dihydromyricetin on several common bacteria in Food

Plants themselves can synthesize certain secondary metabolites with antibacterial activity and act as a defense against microorganisms. Some flavonoids and isoflavones belong to secondary metabolites of this plant and also have certain antibacterial activity. It has been reported that flavonoids, flavonol flavone ligands and apigenin ligands have certain Antibacterial activities. Dihydromyricetin, known as dihydromyricetin (DMY), is also a flavonoid found in the stems and leaves of Ampelopsis grosseden-tata plants. The DMY monomer of effective fraction is above 27%, which has research and development value. Studies have shown that the leaf extract of the ampelopsis grossedentata has a certain inhibitory effect on bacteria and mold, and the antibacterial activity of DMY has not been reported. Therefore, this experiment aims to study the antibacterial effect of DMY on several common bacteria in food, in order to provide reference for food preservation and DMY development.

Food is easily susceptible to suffer microbial contamination and decays. Adding micro-preservatives to foods is a convenient, low-cost, cost-efficient, good-effect method to prevent food from rotting. It plays an irreplaceable role in actual production. At present, commonly used preservatives in production include sorbic acid, benzoic acid, parabens, etc., which have certain toxicity. With the enhancement of people's living standards, it's irresistible that food preservatives with health-care functions need to be developed.

Bacteriostatic experiment and dihydromyricetin 

Dihydromyricetin

Name Dihydromyricetin
Alias Ampelopsin; 27200-12-0; Ampeloptin; (+)-Dihydromyricetin; (+)-Ampelopsin
CAS  No. 27200-12-0
Formula C15H12O8
Weight 320.253 g/mol
Usage Pharmaceuticals/Intermediates
Appearance White powder

 

Milk rancid mixed bacteria: 1% mixed bacteria were inoculated with different amounts of DMY and benzoic acid broth, and cultured at 37 °C on a shaker. The A60 value was determined by timing sampling, and the inoculation medium without preservative was used as a contrast.
Yeast: Using a potato liquid medium at 28 ° C, and other culture conditions were the same as above.
Penicillium citrinum: 1ml of different concentrations of DMY aqueous solution was added to the plates, poured into 15ml culture medium, mixed, made into a plate, and 1ml of sterile water was used as a blank control. After the plate was solidified, the glass rod was used in the alcohol lamp. Three small holes with a diameter of 5 mm or so are melted in different parts of the plate (there is still a layer of medium at the bottom of the hole). In each cave, 0.01 ml of a spore suspension for the mold was poured, and after inoculation, it was allowed to stand still for 2 hours. After the spore suspension was swallowed, it was cultured in a 28 ° C incubator, and the colony diameter was measured every 24 hours. Draw a growth curve of mold.

 

conclusion

Flavonoids are widely existed in natural foods such as vegetables, fruits, and tea, which can reduce the occurrence of cardiovascular diseases, inhibit the self-swallowing of white blood cells, and antiviral and antibacterial effects. Studies have shown that phenolic substances can destroy the integrity of cell wall and cell membrane, resulting in the release of intracellular components from microbial cells. This will cause dysfunction of membrane electron transport, nutrient absorption, nucleotide synthesis and ATP activity, thereby inhibiting microbial growth. DMY is a flavonoid substance extracted from the ampelopsis grossedentata, but its antibacterial effect is rarely reported. In this paper, the inhibitory effect of DMY on several common bacteria in food was studied. The results showed that DMY had significant inhibitory effects on milk rancid mixed flora and mold. The rancid mixed flora of milk is mainly based on bacteria and has strong adaptability. The mixed bacteria group treated with DMY in this experiment shows that the antibacterial effect is enhanced with the increase of concentration, and the antibacterial effect of DMY is the best with .1%. It can be inferred that DMY has an inhibitory effect on bacteria on the mold. As the concentration of DMY increases, the antibacterial activity increases, and the antibacterial effect is best with 0.1% aqueous solution. The antibacterial effect on yeast is not obvious. It may be due to the thick cell wall of yeast cells. It is difficult for DMY to pass through the cell wall to act on the cell membrane, and yeast is a single-cell microorganism. Therefore, DMY has an inhibitory effect on common bacterial milk rancid bacteria and penicillium citrinum in food preservation. In addition, as a food additive, DMY is safe and easy to obtain, and have certain health-care effects on the human body. Therefore, it can be applied to fruits and vegetables susceptible to mold and anti-corrosion and preservation of dairy products that are easily infected by milk rancidity.

Dihydromyricetin, the "soft gold" in flavonoids

The magical effect of rattan tea was interpreted in Western Medicine:
Dihydromyricetin, a special flavonoid extracted from vine tea, is called "soft gold in flavonoids".

Rattan


This kind of substance have various peculiar effects such as scavenging free radicals, anti-oxidation, anti-thrombosis, anti-tumor, anti-inflammatory, etc.. As a special flavonoid compound, in addition to the general characteristics of flavonoids, dihydromyricetin has the following characteristics:

  1. The general flavonoids are nearly insoluble in water, soluble in ethanol (alcohol), while dihydromyricetin is easily soluble in hot water, which means that dihydromyricetin in vine tea can be soaked out with boiling water with better benefits;
  2. In addition to the role of general flavonoids, dihydromyricetin also has the effects of relieving alcoholism, preventing alcoholic liver and fatty liver, inhibiting liver cell deterioration, and reducing the incidence of liver cancer;
  3. Dihydromyricetin has a small molecular weight (320), which makes it easier to pass through the blood-brain barrier and quicker to take effect.

Rattan tea is called the "king of flavonoids"

Rattan tea

The statistics of The research progress of rattan Tea from the Institute of Biological Science and Technology in Hubei University for Nationalities show that the total flavonoids (mainly dihydromyricetin) accounts for 36%-45.1% of the rattan tea. Rattan tea extract pharmacological efficac. According to the Chinese Pharmacopoeia, the total flavonoid content of these substances' comparison with rattan tea are as follows:
                    Flavonoid Content            Multiples
Rattan tea            36%—45.1%                    /
Ginkgo biloba         0.40%                        110
Propolis              1.0%                         45
Eucommia            0.1%                         450
Eucommia            5.0%                          9

The effects of dihydromyricetin

Dihydromyricetin(Generally called Ampelopsin or DIM),  It is a flavanonol with antioxidant and anti-cancer activity, a type of flavonoid. found to have anti-alcohol intoxication effects. It is found in the Ampelopsis species japonica, megalophylla, and Grossedentata; Cercidiphyllum japonicum; Hovenia Dulcis; Rhododendron Cinnabarinum; some Pinus species; and some Cedrus species, as well as in Salix sachalinensis. If you want to buy or know more about this ingredient, please go here. Buy bulk powder

Dihydromyricetin

Name Dihydromyricetin
Alias Ampelopsin; 27200-12-0; Ampeloptin; (+)-Dihydromyricetin; (+)-Ampelopsin
CAS  No. 27200-12-0
Formula C15H12O8
Weight 320.253 g/mol
Usage Pharmaceuticals/Intermediates
Appearance White powder

Dihydromyricetin has significant effects in cleansing blood, reducing blood viscosity, anti-thrombosis, and clearing blood poison. According to The research progress of the pharmacological action of Dihydromyricetin, dihydromyricetin has the following effects:

  1. Dihydromyricetin is a strong antioxidant that can effectively eliminate oxygen free radicals in the body. Its antioxidation can prevent cell degradation and aging, and can also prevent cancer.
  2. Dihydromyricetin can improve blood circulation, lower cholesterol to greatly reduce the incidence of cardiovascular and cerebrovascular diseases. It can also improve cardiovascular and cerebrovascular diseases.
  3. Dihydromyricetin has been proved to reduce blood glucose by 26% and glyceryl triglyceride by 39% in animal experiments. It has a good effect on retinopathy and capillary embrittlement caused by diabetes.
  4. Dihydromyricetin can inhibit the exudation of inflammatory biological enzymes, and improve wound healing and pain relief. It has strong anti-histamine property, which can be used for all kinds of allergies.
  5. Dihydromyricetin has anti-tumor and anti-cancer effects. It has dual functions of prevention and treatment, not only for the tumor but for 14 kinds of cancers such as liver cancer, lung cancer, and stomach cancer.

Tea is precious due to its rare "selenium", Rattan tea with selenium is healthier 

Rattan tea is rich in selenium, which is more beneficial.

selenium

Whether vine tea contains selenium determines the efficacy and quality of vine tea. Enshi is known as the “Selenium of the World”. Its soil and water is rich in selenium so 70% of China's selenium comes from there. The vine tea produced in Laifeng has plentiful selenium, which can meet the selenium intake requirement (50-200ug recommended per person per day).
The research data of the Institute of Biological Science and Technology of Hubei University for Nationalities show that the selenium content of the vine tea produced in Laifeng has 50-100 ug selenium per 100 g of it, which is a unique characteristic of vine tea in Laifeng.

The role of selenium

According to Medical Health, selenium has the following effects:

  1. Enhance immunity. Organic selenium can eliminate free radicals in the body, remove internal toxins, resist oxidation, clear cholesterol, and enhance immune function.
  2. Prevent diabetes. Improve the symptoms of diabetic patients.
  3. Prevent cataracts. Selenium is capable of protecting the retina, enhancing the smoothness of the vitreous, improving vision, and preventing cataracts.
  4. Prevent cardiovascular and cerebrovascular diseases. Selenium is a vital element maintaining the normal function of the heart, and it has a protective and repairing effect on the heart.
  5. Protect the liver. Selenium supplementation can reduce the incidence of liver cancer by 35%, and the incidence of patients who have a history of liver cancer in families is reduced by 50%.

Comprehensive nutrition, recovery without recurrence
Due to the specific climate and natural conditions in the Enshilaifeng area, the vine tea produced it is extremely rich in nutrition:
Firstly, it is rich in a variety of trace elements, iron, copper, zinc, calcium, magnesium, manganese, selenium, sodium, fluorine, iodine, potassium and so on.
Secondly, it is rich in 17 kinds of amino acids.

Rich nutrients help to strengthen the body's resistance and restore health without recurrence.

The influences that methasterone exerts on the brain and how it then makes on sports performance.

The report aims to understand the influences that methasterone exerts on the brain and how it then makes on sports performance. Methasterone is an anabolic steroid usually used by athletes and bodybuilders who wish to get more testosterone as well as muscle fibre. It is a designer steroid and is also called superdrol. Athletes take it with the hope of getting better performance or looking forward to making much money and becoming stronger. Due to the more and more important role sports play in our society, it becomes common to hear that people take steroids so as to get awards in the competition. Athletes are always looking for their advantages which might result in the difference of whether to get the several-million-dollar contract or not. To some extent, this induces people to take steroids.

This report starts with exploring the chemical properties of methasterone, the chemical ingredients and its effects on the brain and other important organs. Then it will talk over and describe how it does actually influence on a person’s sport performance.

Background

It's quite complicated to create methasterone, however, we can summarize it  through several simple steps. The original product, testosterone react with methyl iodide into a methylation reaction, which makes methy group increase. Then hydrogenation takes place in the methanol solution to add a second methyl group. Lastly, hydrogenation occurs again to get rid of the double bond, which creates a final product of methasterone.     

Testosterone chemical structure – retrieved from https://commons. wikipedia.org/wiki/File:Testosterone.PNG)

Methasterone chemical structure - retrieved from (https://en.wikipedia.org/wiki/Methasterone#/media/File:Methasterone.png)

The melting point of methasterone is 223- 225°C and its boiling point is 423.8°C at 760 mm Hg (millimeters of mercury). mm Hg is an old-fashioned unit of measurement for pressure, 70 mm Hg is usually considered equal to one atmosphere, this pressure would be recorded at sea level. Methasterone is white and found as either as powder or tablet. And it is slightly soluble in water.

When a man is taking methasterone,  we can see many obvious changes happened to his body. He will develop much more muscles, smaller testicles, and greater breasts, even becoem bald. If a female takes methasterone, she'll develop larger muscles as well. However, maybe it will disturb her menstrual cycle, narrow her breast, deepen her voice, and even might makes her grow facial hair. 

When athletes take methasterone, it's much easier and quicker for them to grow larger muscles. While they stop taking methasterone, their muscles will narrow again to the original state. Unlike changed muscles, many side-effects won't recover. The female's voice will stay deep, and male's bald state won't disappear. These side-effects happened due to all the extra existing testosterone in the body. Other side-effects, such as the growth of a man's breast occurs because of more intracorporal testosterone which naturally tries to balance the relationship between estrogen (the female reproductive hormone) and itself.     

Except the changes of the bodies, these people and anyone paying enough attention to them will notice that intense but invisible changes happened in their bodies. However, as for the steroid takers, it will make them worse within a long period. It can do harm to liver and kidneys, increase heart rate, raise the chance of heart attack, and impair your immune system. 

The evidence scientists have collected about the effects of steroids as general topic on the brain is quite limited. As we all know, it can cause changes of behaviors. Using steroids will lead to aggressive and violent outbreaks. When you stop taking the steroid, it tends to cause depression, even leads to suicide events.       

When adolescent animals were under test, it was indicated that it disturbed the normal operation of aggression circuits throughout the brain, the circuits responsible for activating aggression were amplified and the ones responsible for inhibiting aggression were paused. This causes everything to go beyond the natural balance, then the high-level aggression was induced.

The facts has proved that taking steroids will affect the anterior hypothalamus which is the part of the brain responsible for sending out hormones. This is because steroids can replicate the hormones our body has already makes, while steroids just give us that of higher dosages.       

Steroids also have an effect on neurotransmitters' function, this is owing to the testosterone in the steroid being distributed to many parts of the brain, including the hypothalamus,  the part of the brain which controls appetite, blood pressure, mood control and reproductive system. The testosterone from the steroid will disturb the natural occurrence of testosterone in the body when it is sent to the hypothalamus.       

Essentially speaking, the function of methasterone is to enable muscle cells in the body to produce more protein, which can be combined with exercises to promote large muscle growth. They can also prevent the combination of cortisol and muscle cells receptor sites. This reduces breakdowns in processing, while less breakdowns mean less muscle fatigue, which enables a quicker recovery and further development of muscles. This also proves that taking methasterone can help people exercise and recover quickier so that they can exercise more often and get muscles easier.

Discussion

This report aims to better understand how methasterone affects sports performance. By now, the study has covered methasterone’s chemical properties, chemical ingredients and effects it exerts on the brain. However, does methasterone have anything to do with sports perforamance? How does it affect athletes' performance in their chosen sports? In terms of this, we will discuss it in detail. What on earth can methasterone do to improve your performance?     

All the information provided so far has nothing to do with sports performance, so let's consider it in a certain perspective. First of all, let's imagine an elite male athlete training up for a big event and doing so in an entirely legal and natural condition. He will work together with a trainer to make full use of his training. Each training he will push his body to either improve aerobic or anaerobic fitness. Whichever he choose, He will work hard and his muscles will be sore afterwards. Of course, he will get rid of his lactic acid developed in his muscles after 48 hours on average. During that time, his muscles will repair themselves causing them stronger.  

Now let's imagine another male elite athlete, while he’s taking methasterone, which is illegal and unnatural. He will have longer training time, higher work efficiency, and less fatigue in his muscles. After the training he will only spend 24 hours on recovery, so he will be able to exercise again in a quicker way. As for him, when his muscles repair themselves, they get stronger than ones without using the methasterone.

They all mean that when it is used on performance day, the athlete taking methasterone will be able to have larger and fitter muscle. He’ll be able to work harder on the future days as he continues taking methasterone. Besides, if he takes part in a several-day event he will be able to perform at his best over a longer period of time.

The example not only suits males, but also applies to females. They will also get the same benefits from taking the substance. Both sexes would also lose the muscle mass over the course of taking methasterone and both would have the negative side effects.

Conclusion

In the report we talked over chemical properties of methasterone, its chemical ingredients includes how to make the designer drug. The positive and negative effects impact brain and other vital organs. It was then discussed how exactly it influence sports performance. Now, we can draw a conclusion that methasterone is a highly complicated drug to manufacture, containing a starting product of testosterone. It has a very long-term dangerous side effects to your body, but only a little is known by scientists as to what actually goes on in the brain in relation to steroids. Though it will allow you to get better preparation for a sports event, however, you will be left with both physical and mental hurt for a long time after using it.

Public Education Piece

Our public education piece is a video to provide the general public with the information learned during this research assignment.

98%min purity Methasterone Superdrol Anabolin is used to increase RBC For Bodybuilding.

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Detailed specification of Methyldrostanolone is as follows. 

Synonyms: 2,17-Dimethyldihydrotestosterone; 17-hydroxy-2,17-dimethylandrostan-3-one
Superdrol Alias: 2,17-Dimethyldihydrotestosterone , 17-hydroxy-2,17-dimethylandrostan-3-one, Methasteron, Superdrol,17a-Methyl-Drostanolone
Superdrol CAS: 3381-88-2
Superdrol MF: C19H30O2
Superdrol MW: 290.44
Superdrol Assay: 98.9% min.
Superdrol Density:1.04g/cm3
Superdrol Boiling Point: 423.8°C at 760 mmHg
Superdrol Flash Point:180.8°C
Superdrol Delivery: Express courier.
Superdrol Character: White crystalline powder.
Superdrol Usage: pharmaceutical material, Steroid hormone, Anabolin. As a male hormone and anabolic hormones.
Superdrol Packing: foil bag or tin.
Superdrol Certificates:ISO 9001, GMP
Superdrol Shipment Way: EMS, Fedex, DHL, TNT, UPS
Superdrol Payment method: T/T,western union, money gram, bitcoins, bank transfer.
Methyldrostanolone – Highly Anabolic, with Fewer Androgenic Qualities
You can get some incredible results of Superdrol which is still one of the most popular oral steroids. One reason that bodybuilders love Superdrol is that it’s anabolic without causing androgenic side effects (hair loss, acne, body hair). Now, this does not mean that methasterone have no significant androgenic properties. However, according to the research in 1969, it was shown that methasterone has a “Q-ratio” of 20, meaning it’s “400% as anabolic and 20% as androgenic.”

Methasterone takes effect really fast and can be used as a Kickstarter
Superdrol which can begin with significant results in just the second week of use. Due to the fast-acting Superdrol results, it’s commonly used as a kickstarter when stacked with long-ester injectables like testosterone enanthate/cypionate, trenbolone enanthate and Boldenone undecylenate. There is a common experience that users will add up to 10 pounds in lean muscle during their initial 4-6 weeks, followed by more gains when the long-ester drug(s) really kick in.

Superdrol Application:

Superdrol is an anabolic substance, meaning it promotes protein synthesis, and thus muscle strength. When muscles become stronger, they grow. Finally, Superdrol users experience a large number of gains in muscle mass because their muscles become much stronger.
Another advantage of using Superdrol is that it won't turn into estrogen.
Many prohormones are available to begin as a testosterone-like substance in the body, but then eventually turn into estrogen through a process called aromatization. Estrogen causes decreased strength, muscle loss and fat gain. Thus, it is a pusher of the exactly opposite traits someone who is taking Superdrol would want. These characteristics appears after one stops taking the compound. Using Superdrol, however, the aromatization process will never happen. The compound does not turn into estrogen in the body, meaning much of the muscle gain and fat loss one experienced while taking it will remain after dosing ends.
It is suggested that Superdrol should be taken daily, preferably with food, and the dosage should not exceed 2 capsules per day which is enough to keep blood serum levels well above baseline with this particular drug. Superdrol cycles are best to run for 2-4 weeks, and should not last for over 4 weeks.

 

Superdrol Description:

Methasterone (Superdrol, methasteron, and methyldrostanolone) is an oral anabolic steroid. Superdrol, also called Methasterone, is an anabolic steroid. In terms of bodybuilding/athletic purposes, Superdrol increases testosterone levels, which induces notable increases in body shape and size, mainly due to its ability to increase the number of muscle fibers.
These benefits not only make Superdrol a formidable androgen, but also contains other conventional steroid properties, for example, increased red blood cell (RBC) production; improved endurance during exercise via better lactic acid clearing; enhanced oxygen and nutrient delivery to working muscles for greater stamina; better muscle glycogen restoration after exercise for faster recovery; and the inhibition of catabolism (muscle destruction).

 

Metamizole's latest usage and dosage description in the EU and other developed Countries

New instructions on the use and dosage of the painkiller Metamizole

The European Medicines Agency (EMA) recommends that the dose of Metamizole should be used consistently during pregnancy and lactation in all EU member states. This need stems from obvious differences and inconsistencies in the drug directives of several EU countries, as the drug occasionally causes serious side effects.

Metamizole

Specifically, the EMA has reviewed the human use (CHMP) for pharmaceutical products and recommends a uniform contraindication for daily maximum doses of pregnancy and lactation in the European Union. Metamizole is an analgesic that can treat severe pain and fever while other treatments are beyond control.

Recommended usage and dosage

The EMA defined a maximum dose as 1000 mg to 4 times a day, ie a maximum dose of 4000 mg per day, orally. For patients aged 15 years and older, treatment should start with the recommended minimum dose and only increase when needed. The injection dose should not exceed 5000 mg.

Young patients should be dosed based on body weight, but some products may not be suitable due to their effectiveness. For pregnancy and breastfeeding, a one-time dose is acceptable during the first 6 months of pregnancy, only if other analgesics are not available. But the drug should not be used during the last trimester of pregnancy due to the circulation and function of the kidneys of the fetus.

The Metamizole USA should not be used during breastfeeding because the baby can get a high amount of protein related to its weight.