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Etamsylate is easily soluble within water, soluble in ethanol, slightly soluble in acetone, insoluble in chloroform plus ether. It is hygroscopic and easily deteriorates whenever exposed to light. Odorless, bitter. Phenolsulfonate will be able to decrease capillary permeability, enhance platelet perform and adhesion, promote platelet release of coagulation energetic substances, shorten coagulation time and stop bleeding. This may be used to prevent bleeding before and right after surgery and various vascular factors. Effective for
Etamsylate is a hemostatic agent, This is believed to work by increasing capillary endothelial resistance and marketing platelet adhesion. It furthermore prevents the biosynthesis plus action of these prostaglandins which cause platelet disaggregation, vasodilation, and increased capillary permeability.
Etamsylate boosts the number, aggregation, and adhesion of platelets and encourages the release of clotting actives from platelets. It may also speed up blood clot contraction, reduce coagulation time, and also enhance capillary resistance and reduce capillary permeability. For the prevention and treatment associated with bleeding before surgery.
Prophylaxis and control over haemorrhages from small arteries, neonatal intraventricular haemorrhage, capillary hemorrhaging of different etiology, which includes: menorrhagia and metrorrhagia
It also inhibits the particular effects of the prostaglandin mediated vasodilatation and increased capillary permeability, thereby decreasing edema secondary to capillary leakage. By inhibiting the particular effects of prostaglandins, etamsylate may exert a direct effect by closing the obvious ductus and thereby increasing cerebral blood flow.